Epilepsy is considered to be one of the major neurological disorders among people as per the findings of Epilepsy foundation.
It has been found by the medical researchers that CBD is a very effective treatment for even difficult types of epilepsies, which cannot be easily treated by using conventional medical treatments.
Although for past decades, plenty of debates were going on among the medical community, as far as the effectiveness of the cannabis extracts were concerned. This was particularly regarding the treatment of neurological conditions like epilepsy.
Companies, who are manufacturing pharmaceutical based cannabis products, claim that purified extracts are quite effective however few other studies have established that full-spectrum extracts can be much more effective for treating epilepsy.
Potential benefits of cannabinoids for epilepsy
In spite of various research results that we have seen, as far as various effects of cannabinoids for epileptic conditions is concerned, it is still very difficult to explain about the exact mechanisms involved for treatment of epilepsy.
Usually seizure conditions are incredibly complex. Also, the reasons for these problems are generally due to involvement of multiple organ dysfunctions and all the combinations to produce symptoms.
Hence to exactly pinpoint which part of such interaction is actually improved due to cannabinoid is very difficult to identify.
Following are the present theories based on various clinical trials and also findings of various research done by scientists in this field.
- Vanilloid receptor activity
With CBD and CBDV, there is activation of TRPV1 vanilloid receptors, present in our brain. As TRPV1 vanilloid receptors are overactivated due to any reasons, it will induce epileptic seizures.
It has been found that CBD and CBDV can control various over activities of this receptor present in our brain that can cause very severely, which may lead to fewer seizures.
Experiments were done on epileptic-induced rodents, and they were given various kinds of concentrations of CBD.
Those who were given highest-dose group i.e. 100 mg per kg, displayed significant amount of improvement in their muscle contractions taking place during seizures.
CBD as well as many other cannabinoids present in cannabis plant displayed having broad non-specific neuroprotective type of effects on our brain.
Few of such neuroprotective effects are initially thought to be some way responsible for powerful anti-epileptic activity of CBD.
CBD is found to be protective for few other neurological conditions, which are as follows:
- Alzheimer’s disease
- Multiple sclerosis
- Parkinson’s disease
- Prion disease
- Spinal cord injury
Like with most of the neurological disorders, in case of epilepsy too, inflammation is a huge factor.
Plenty of evidence suggests that CBD can be a very effective anti-inflammatory compound meant for our brain, which is potentially alleviating one significant factor for various neurological disorders e.g. epilepsy.
CBD is found to be quite effective because of its fat-soluble nature that allows the CBD to pass through our blood – brain barrier very efficiently.
Also, it can offer anti-inflammatory effects with the help of few different immune-regulating cells and inflammatory messengers.
To obtain most out of the CBD for epilepsy, it is necessary to use high-quality and full-spectrum CBD extract. Also, opt for high-potency dose.